Many frail older adults are slim, weak and under nourished; this part of frailty remains a critical concern in the old age. However, there is also strong conformation that excessive obesity contributes to frailty, therefore, present study was conducted to assess the Relationship between Obesity and Frailty in Older Population of Karachi, Pakistan. A cross sectional survey was conducted in different hospitals of Karachi, Pakistan from January to March 2018. BMI was measured by standard procedure in already diagnosed 377 patients of Fraility (mild and sever) and SPSS version 23 was used to analyze the data. The majority were (n=215, 57%) male and having age between 61 to 63 years (n=75, 19.9%), overweight (n=151, 40%) and Obese were (n=37, 9.8%) no significant correlation was found between obesity and frailty. This Study concluded that there is no significance of obesity on Fraility, because mostly the government facilities are being attended by the poor patients and the rich patients who may have the obesity along with Fraility may go to the private institutes.